Hi Billy, answering to your PM, first of all I mean I'm not using D-Fend or any other program. Also, are you running DOSBox in a window or fullscreen? For me it works both ways, but if you're in fullscreen try pressing Alt+Enter to go into windowed mode, in case it works that way.
The game works for me with the default configuration of DOSBox. That means you can delete your existing configuration file, by clicking on the "reset options" shortcut on your "start menu > programs > DOSBox-0.74 > options" folder. (Or if you have edited it and don't want to lose it, you can move it someplace else.) So there's no configuration file whatsoever that I could show you.
Then take the "4x4.exe" file that starts the game, and drop it onto the DOSBox shortcut (either on the desktop or in the start menu) like
this post explains (either drag 'n drop or copy-paste it).
This works for me, let us know if it doesn't for you.