well, i'm not sure right now but i think that settlers 2 used ipx for multiplaying
which means that you can play ipx multiplayer with your friends using dosbox, that one can create a virtual ipx network via regular tcp/ip
of course, you'd need to have a dos version.. i don't know how they ported the dos version to windows on gog where it's sold..
but i'm pretty sure they're using dosbox too, so if you managed to take out the original dos files and set stuff up manually you'd be able to create an ipx virtual connection easilly
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