Recommended readings are
here and
here.
Tell me if you need further help after reading those. Before I knew the existance of DOSBox I used those two links to help me bring Apocalypse to work on my XP machine. It can be done but it's really a pain, and you'll need a lot of trial and errors.
And if you do manage to get it to work, don't start any other application before running it. You should restart your computer to be sure it won't crash randomly before playing it.