And let's not forget that certain titles are for sale as well.
I guess it wouldnt be too difficult to prove at a court of law, how a fan who made Space Quest 7 caused a decrease of sale for a Space Quest Space Adventure pack (or something) that the copyright holder was selling. Might not be true, but it could stand up in the court of law. So if you're asking about freeare fan made games, because you'd like to make and publish one - I suggest you change your characters and the title (Cosmic Quest with Willy Rogerco, or something).
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