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[TheChosen]

http://www.videogaming247.com/2008/1...ndhand-market/

“The secondary market is a huge issue in the United States. Our primary retailer makes the majority of its money off of secondary sales, and so you’re starting to see games taking proactive steps toward that by… if you buy the retail version you get the unlock code,” he said.
“I’ve talked to some developers who are saying ‘If you want to fight the final boss you go online and pay USD 20, but if you bought the retail version you got it for free’. We don’t make any money when someone rents it, and we don’t make any money when someone buys it used - way more than twice as many people played Gears than bought it.”

This is actually more of console stuff, but it could spread on PC games as well, if it ever happens.