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Eating a karmic corpse gives you luck and fate smiles, and removes cursing and dooming. Attacking a karmic being curses and then dooms you. Wearing a ring of Karmic Resistance prevents this from happening when attacking with melee, although the B/U/C status changes, and the ring will eventually break.

Read the guidebook. www.andywlms.com/adom. There is a section on karmic beings.