I find Opera to be quite bloated as compared to Firefox. And furthermore, it is missing a few features which I find essential, such as being able to Cmd-~ to cycle through my windows. Plus, the rendering engine does some odd things to a good many webpages, especially with text size. And the popup blocker is too restrictive (blocks links that open in new windows). Firefox has better plugins too.
So, I prefer firefox. But Opera's certainly better than IE.
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