.... should have a 'restore to defaults' or similar button somewhere in the settings,
if not: crappy and totally worthless bad coded software.
[edit]
Don't know about that 'calibrize' thing but nvidea has a 'delete' profiles option in my nVidea control panel:
And yes, uninstall that calibrize thing, you can handle everything in the nVidea control panel, eventually use the 'advanced' mode for further fine tuning, if needed.