You've got Sound Blaster 16 on both lists, try using that setting.
If that doesn't work, change soundcard emulation in DosBox.conf to Sound Blaster Pro 2 (
sbpro2) and adjust the configuration accordingly. (
more on dosbox.conf here).
As for saving the game... well, haven't played that one, so can't know for sure, but look around the menus. Often, the save/restore options use either a floppy or a computer for their icon.