You might want to check out
the official DosBox FAQ, and particularly
this part of it. It is quite helpful for users unfamiliar with DosBox.
Also, don't bother with D-Fend. It's known to cause crashes every now and then. If you want to know how to create an easy double-click-to-run-the-game shortcut, feel free to check the WIP guide I posted in
this thread