Maybe the CD has some sort of copy protection and the image isn't 100% accurate?
I've seen some games that check the CD label and won't run if the label is wrong. Might be the first thing to try:
http://www.vogons.org/viewtopic.php?...art=20#p118149
You'll have to find out what the correct label is for this to work. And of course it's possible that the CD label is not the problem and this won't help at all.