Are you running windows 7 64x? Frankenstein is a 16 bit game. Therefore it can't run on a 64 bit system. If you have the 3.x version of the game you can run it on dosbox. To run a windows 3.x game on dosbox you must have the 3.x OS running on dosbox. Go to
www.dosbox.com on how to run 3.x games on dosbox.