you can of course run some anti virus program
however, i'd just check the location and description of mshta.exe. then search for "runonce" keys in regedit; once you find a runonce key you will also have a "run" key nearby, check the mshta.exe value out there. notice that there are multiple "run" keys in your registry
if it's not there you can also check it under services in control panel/administrative tools
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